Padaley Lodge is located at Lyrup, a small horticultural settlement in the Riverland of South Australia.
Lyrup is surrounded by the major Riverland towns of Berri (12kms), Loxton (28kms) and Renmark (15kms) and the Lyrup Flats form part of the Murray River National Park.
A ferry operates (at no charge to passengers) 24 hours a day from the Lyrup riverfront and is one of eleven cable ferries left operating in South Australia.